Mutant Prevention Concentration of Gemifloxacin for Clinical Isolates of Streptococcus pneumoniae
نویسندگان
چکیده
منابع مشابه
Mutant prevention concentration of tigecycline for clinical isolates of Streptococcus pneumoniae and Staphylococcus aureus.
BACKGROUND The mutant prevention concentration (MPC) reflects the antimicrobial susceptibility of the resistant mutant subpopulations present in large bacterial populations. In principle, combining the MPC with pharmacokinetic measurements can guide treatment to restrict the enrichment of resistant subpopulations, just as the MIC is used with pharmacokinetics to restrict the growth of bulk, sus...
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Sir, Tigecycline is a therapeutic option for multidrug-resistant Acinetobacter baumannii and Klebsiella pneumoniae infections. Recently, tigecycline-non-susceptible A. baumannii and K. pneumoniae have been reported in patients receiving tigecycline. Despite several reports concerning in vitro and in vivo susceptibility of bacterial pathogens to tigecycline, there is a paucity of data regarding ...
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Dear Editor, Klebsiella pneumoniae (K. pneumoniae) is one of the most important causes of healthcare-associated infections, especially among hospitalized patients [1]. Since most clinical isolates of K. pneumoniae are resistant to fluoroquinolones and carbapenems, clinicians have to use tigecycline as the last resort. Unfortunately, the prevalence of tigecycline-resistant K. pneumoniae seems to...
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This review focuses on the activity of gemifloxacin, a new respiratory fluoroquinolone, against the two most important bacterial pathogens associated with lower respiratory tract infections, namely Streptococcus pneumoniae and Haemophilus influenzae.
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2003
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.47.1.440-441.2003